MedicineNews.net - Medical Updates

Sprycel linked to risk of pulmonary arterial hypertension

The FDA ( Food and Drug Administration ) has informed the public that the leukemia drug Sprycel ( Dasatinib ) may increase the risk of a rare, but serious condition in which there is abnormally high b ... read article

Anti-inflammatory drugs linked to risk of atrial fibrillation or flutter

Non-selective non-steroidal anti-inflammatory drugs ( NSAIDs ) and selective COX-2 inhibitors are linked to an increased risk of atrial fibrillation or flutter. These drugs have already been linked ... read article

Lorcaserin causes significant weight loss and improves maintenance of weight loss

The results from the two-year BLOOM ( Behavioral modification and Lorcaserin for Overweight and Obesity Management ) trial have been published in the New England Journal of Medicine ( NEJM ). Lorcaser ... read article

EMA: the use of Modafinil should be restricted to the treatment of narcolepsy

The European Medicines Agency ( EMA ) has recommended restricting the use of Modafinil-containing medicines. Modafinil should only be used to treat sleepiness associated with narcolepsy. Physicians ... read article

Votrient in the treatment of advanced renal cell carcinoma and ovarian carcinoma

GlaxoSmithKline ( GSK ) has announced results from ongoing Phase II studies of Pazopanib ( Votrient ) in advanced or metastatic renal cell carcinoma ( RCC ) and ovarian cancer. Pazopanib is an ora ... read article

Europe: Vpriv approved for type 1 Gaucher disease

European Commission has granted marketing authorisation for Vpriv ( Velaglucerase alfa ), a human cell line derived enzyme replacement therapy ( ERT ) for the long-term treatment of type 1 Gaucher dis ... read article

Angiotensin receptor blockers: Benicar associated with cardiovascular events

The FDA ( Food and Drug Administration ) is evaluating data from two clinical trials in which patients with type 2 diabetes taking the blood pressure medication, Benicar ( Olmesartan ) had a higher ra ... read article

Obesity and overweight: Sibutramine is contraindicated in patients with history of cardiovascular disease or uncontrolled hypertension

The FDA ( Food and Drug Administration ) has reviewed additional data that indicate an increased risk of myocardial infarction and stroke in patients with a history of cardiovascular disease using Sib ... read article

EMA: restricting the use of Modafinil-containing medicines

The EMA ( European Medicines Agency ) has recommended restricting the use of Modafinil-containing medicines. The medicine should only be used to treat sleepiness associated with narcolepsy. Physicians ... read article

Risk of cancer associated with angiotensin-receptor blockers

Angiotensin-receptor blockers ( also known as sartans ) are a widely used drug class approved for treatment of hypertension, heart failure, diabetic nephropathy, and for cardiovascular risk reduction. ... read article

Pediatric patients: use of antipsychotics associated with significant weight gain

Many pediatric and adolescent patients who received second-generation antipsychotic medications experienced significant weight gain, along with varied adverse effects on cholesterol and triglyceride l ... read article

HEAAL Study: higher dose of Losartan significantly reduced deaths and hospitalizations due to heart failure

In an investigational study, Losartan ( Cozaar ) 150 mg, administered once daily, significantly reduced the risk of all-cause death or hospitalization due to heart failure compared to a lower 50 mg on ... read article

Antipsychotic drugs: use of Olanzapine by children and adolescents associated with high weight gain

Many pediatric and adolescent patients who received second-generation antipsychotic medications experienced significant weight gain, along with varied adverse effects on cholesterol and triglyceride l ... read article

Antipsychotics may contribute to inflammatory processes

The treatment with a number of antipsychotic medications is associated with weight gain, and for some, hyperglycemia and hyperlipidemia. This cluster of metabolic side effects may contribute to the r ... read article

ACE inhibitors and angiotensin II receptor antagonists: recommendations on use during pregnancy and breastfeeding

Angiotensin converting enzyme ( ACE ) inhibitors and angiotensin II receptor antagonists ( sartans ) are licensed for a range of conditions including hypertension and may be particularly suitable for ... read article